R&D Personalized medicine: DYNAPRED – DynaPred
Dynakin R&D activity is mainly directed towards individualized treatment systems through the development of methods and products for prediction of the optimal dose, or posology scheme, for drugs with a narrow therapeutic range mostly in chronic or costly therapies and in pediatrics.
DynaPRED® is an application designed to be accessible on a server via the web with a mathematical estimation core (stand alone proprietary executable and dynamically loaded library). DynaPRED is the Bayesian estimator functionality of Dynakin’s own development of a maximum likelihood estimation software package for PK /PD, Dknonlin®. Dknonlin – DynaPRED has been optimized to perform real-time estimation offering the possibility of fully interactive screen (touch screen) for trial and error / simulation exploration of dosing regimen scenaria.
Funded project Spanish Government #SME-2017-1008-1 (The platform for personalized pharmacotherapy).
Funded project CDTI #INNO-20171110 (Development of a platform to streamline dosing regimens in older adults in cooperation with the University of Florida).
Funded project CDTI #TRINS- IDI-20170710 (Treatment individualization software).
Funded project SPRI (Basque government) #DRUGFREE- ZL-2019-00090 (High-throughput plasma protein binding assay).
